Cryptogenic Organising Pneumonia As The Initial Presenting Manifestation of SLE
نویسندگان
چکیده
Cryptogenic Organising Pneumonia (COP), also called idiopathic Bronchiolitis Obliterans Organising Pneumonia( BOOP), is a distinct entity among the idiopathic interstitial pneumonias defined histopathologically by intraalveolar buds of granulation tissue. The etiology includes idiopathic, infectious, drug induced radiation induced and connective tissue diseases. Organising pneumonia occurs particularly in patients with dermatomyositis-polymyositis where it may be the presenting manifestation, and rarely in SLE, rheumatoid arthritis, scleroderma and other connective tissue diseases. We describe a 30 yr old lady who initially presented with respiratory symptoms, not responding to antibiotics. She was subsequently diagnosed as SLE and HRCT thorax showed consolidation involving both lung fields. A percutaneous lung biopsy revealed features of Cryptogenic Organising Pneumonia.
منابع مشابه
Cryptogenic organising pneumonia presenting with spontaneous pneumothorax and the value of procalcitonin: A case report
Cryptogenic Organising Pneumonia (COP) is a relatively rare condition and can be difficult to differentiate from Community acquired pneumonia (CAP). We report two cases which demonstrate the importance of considering this differential diagnosis in patients with spontaneous pneumothorax who have raised inflammatory markers or lung infiltrates. Our report highlights the value of serum procalciton...
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First, histology is described as follows: ‘‘...diffuse intraalveolar exudate of granular, fibrinous material...’’. Organising pneumonia pattern, the histological hallmark of cryptogenic organising pneumonia, is characterised by intraalveolar buds of granulation tissue. Recently, a new anatomoclinical entity has been reported by BEASLEY et al. [2] as ‘‘acute fibrinous and organizing pneumonia (A...
متن کاملCryptogenic organising pneumonia or acute fibrinous and organising pneumonia?
First, histology is described as follows: ‘‘...diffuse intraalveolar exudate of granular, fibrinous material...’’. Organising pneumonia pattern, the histological hallmark of cryptogenic organising pneumonia, is characterised by intraalveolar buds of granulation tissue. Recently, a new anatomoclinical entity has been reported by BEASLEY et al. [2] as ‘‘acute fibrinous and organizing pneumonia (A...
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Organising pneumonia (OP) is a distinct type of interstitial lung disease, because it can also be seen in association with several conditions such as infections, drugs, and connective tissue diseases. An association of OP with rheumatoid arthritis (RA) has also been described. Joint manifestations of RA usually precede lung involvements by several years; however, in less than 10% of cases of RA...
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Organising pneumonia, defined by intraalveolar buds of connective tissue, may be a disorder secondary to a determined cause (infectious agents, drugs) or occurring in a specific context (as the connective tissue disorders). It may also be a cryptogenic interstitial pneumonia with characteristic clinical and imaging features and especially an excellent response to corticosteroids.
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